Big Gainers & Losers (DNDN, ACOM, NEI, BKS, AEO)

Dendreon Corporation (NASDAQ: DNDN) surged 39.08% to $10.57 in the morning hours after the company said that fourth quarter gross product revenue was approximately $82 million. Full-year gross revenues from PROVENGE sales were approximately $228 million.

Ancestry.com Inc (NASDAQ: ACOM) climbed 16.53% to $26.65 in the early hour after the company reported that it ended the fourth quarter with 1,703,000 paying subscribers, above the company’s guidance of 1,685,000 — 1,695,000 subscribers. The company also said that it currently expects 2012 revenue growth in the mid-to-high teens.

Network Engines, Inc. (NASDAQ: NEI) increased 18.37% to $1.23 in the morning hours after the company provided revised and improved expectations for the first fiscal quarter, the period ended December 31, 2011. The management now expects fiscal first quarter net revenues in the range of $68 million to $70 million , greater than the original guidance of $58 million to $63 million provided on November 10, 2011 .

Barnes & Noble, Inc. (NYSE: BKS) plunged 23.76% to $10.33 in the morning hours after the company the company said it expects fiscal 2012 digital content sales to be approximately $450 million. By fiscal 2012 year-end, based upon forecasted device sales, the company expects annualized U.S. digital content sales will achieve a run-rate of approximately $700 [million to] $750 million.

American Eagle Outfitters (NYSE: AEO) plummeted 14.18% to $13.04 in the morning hours after the company announced that total sales for the two month November/December period ended December 31, 2011 increased 15% to $887 million, as compared to $771 million for the same period ended January 1, 2011. Comparable store sales increased 12%, compared to a 7% decrease for the same period last year.

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